Skip to main content

Featured five-star hotel destinations

Destination inspiration for your trip – find a five-star hotel

The best five-star hotels in Panama

Check out our pick of great five-star hotels in Panama

Filter by:


Review score

Superb: 9+ Very good: 8+ Good: 7+ Pleasant: 6+
Our top picks Lowest price first Star rating and price Top reviewed

See the latest prices and deals by choosing your dates.

Amid the financial district of Panamá, Bristol Panama, a Registry Collection Hotel

has a spa centre and a sauna for guests to enjoy a massage, or they may use the fitness centre after a day’s work. Free WiFi is available. There was a good selection for breakfast + we liked the optional dishes too. Adored the little boxed biscuit on the bedside table during turn down service. Very friendly staff all round but the restaurant staff imparticular made us feel special! Definitely coming back ☺️

Show more Show less
9.2
Superb
1,105 reviews
Price from
US$225
per night

Set in Panama City and with Ancon Hill reachable within 4 km, Hotel La Compañía Casco Antiguo features concierge services, allergy-free rooms, a terrace, free WiFi throughout the property and a restaurant. This 5-star hotel offers a 24-hour front desk and a business centre. The hotel offers an outdoor swimming pool, fitness centre, nightclub and room service. Location. Restaurants and bars. Room. Breakfast. Friendly staff.

Show more Show less
9.4
Superb
498 reviews
Price from
US$345
per night

Situated in Panama City, 4 km from Ancon Hill, Sofitel Legend Casco Viejo, Panama City features accommodation with an outdoor swimming pool, private parking, a fitness centre and a garden. Featuring a restaurant, the property also has a terrace and a bar. The accommodation offers a 24-hour front desk, airport transfers, room service and free WiFi. This hotel is superb and we will definitely stay again

Show more Show less
9.4
Superb
831 reviews
Price from
US$364.50
per night

Located in Panama City, 3.5 km from Estadio Rommel Fernandez, The Santa Maria, a Luxury Collection Hotel & Golf Resort, Panama City provides accommodation with free bikes, free private parking, an outdoor swimming pool and a fitness centre. With a garden, the property also features a terrace, as well as a bar. The accommodation offers a 24-hour front desk, a shuttle service, room service and free WiFi throughout the property. This is an absolutely stunning property with beautifully rooms, amazing restaurant, fantastic pool. Location is close to the airport on a very nice golf and country club. Calm and peaceful, ideal for an active time. Professional gym on premise as well.

Show more Show less
9.4
Superb
457 reviews
Price from
US$205.82
per night

The luxury 20-storey Hyatt Regency Panama City is set in central Panama City, 1 km from Bahía de Panamá Bay and its port. It features an outdoor pool, spa, and rooms with seating areas.

Hyatt Regency Panama City has attractive, traditional décor with wooden furnishings. Each air-conditioned room has a flat-screen TV, a desk and a marble bathroom. The property is a beautifully designed modern hotel in a great location. We loved the Amado coffee shop and market on the first floor of the hotel. The coffee, pastries, juices, etc. sold at the Amado were delicious. Our room was designed beautifully and very spacious.

Show more Show less
9.1
Superb
107 reviews
Price from
US$199
per night

Situated in Panama City, 6.4 km from Ancon Hill, La Residence Panamá features accommodation with a fitness centre, free private parking, a shared lounge and a restaurant. This 5-star hotel offers room service, a 24-hour front desk and free WiFi. Guests can have a drink at the bar. Great property and staff. Hotel is quite new, so amenities are modern and well thought out. The staff are all lovely, welcoming and accommodating to guest needs. Jorge (front desk) and Edison (door man) were always available when we needed anything. Location is convenient to restaurants, sightseeing and shopping. The loft was perfect for our needs; two separate bedrooms and bathrooms (upstairs and downstairs) offered the privacy and comfort needed for three adults. Full kitchen and a washer dyer combo.

Show more Show less
9.9
Exceptional
8 reviews
Price from
US$148
per night

Set 3.7 km from Ancon Hill, Hotel Plaza Herrera offers 5-star accommodation in Panama City and features a bar. Among the facilities of this property are a restaurant, room service and a 24-hour front desk, along with free WiFi throughout the property. Private parking can be arranged at an extra charge. This hotel is brand new, renovated on a restored building in the Casco area of Panama city. The location is amazing, on a quite square, but a minute walk from all the restaurants and attractions of the area. Stayed as a family in a big room, two floors, two bathrooms, huge balcony with a view. Facilities are elegant and beautiful. Breakfast is delicious, with free choice from an a-la-carte menu. Would definitely return here.

Show more Show less
9.3
Superb
24 reviews
Price from
US$330
per night

Located in Panama City, 8 km from Bridge of the Americas, Waymore Hotel Spa & Casino provides accommodation with an outdoor swimming pool, free private parking, a fitness centre and a restaurant. Each accommodation at the 5-star hotel has city views, and guests can enjoy access to a bar and to a casino. The accommodation offers a 24-hour front desk, airport transfers, room service and free WiFi throughout the property. Clean, spacious, well maintained, quality toiletries, large selection at breakfast, large comfortable bed

Show more Show less
8.6
Fabulous
2,161 reviews
Price from
US$105
per night

Located in Panama City, 6.5 km from Ancon Hill, Gran Evenia Panamá Hotel provides accommodation with an outdoor swimming pool, free private parking, a fitness centre and a garden. Featuring a shared lounge, the 5-star hotel has air-conditioned rooms with free WiFi, each with a private bathroom. The hotel features city views, a terrace and a 24-hour front desk. Everything is so perfect,staff is super friendly and helpful.Rooms are big,clean and fancy.Breakfast is super tasty,huge choices …Pool is clean and furniture around is so comfortable.We definitely recommend this hotel,10/10😍

Show more Show less
8.6
Fabulous
1,261 reviews
Price from
US$87
per night

Offering an outdoor pool and spa centre, Central Hotel Panama is set in the historic centre of Panama City, 200 metres from Presidential Palace. The hotel has a sauna and fitness centre, and guests can enjoy a meal at the restaurant. Private parking is available on site. The hotel is so beautiful and spacious. We love the design and the architecture so much and it somewhat makes us feel went back to the old days. The location is just at center. The staff at reception is very very nice. He told us so much about the history and stories of the hotel, and also gave us some suggestions for what to see in Cisco Viejo. The lobby bar pianist is wonderful and plaid the music so beautiful. We like everything in the hotel.

Show more Show less
8.6
Fabulous
1,574 reviews
Price from
US$394.40
per night

Most booked five-star hotels in Panama this month

FAQs about five-star hotels in Panama

Five-Star Hotels that guests love in Panama